RSC has worked with several outstanding genetics labs, including the following:
1. Reprogenetics is a private genetics lab that has been specializing in PGD and PGS since 1991. Their founders, Dr. Santiago Munné and Dr. Jaques Cohen, have been leaders in the field. Reprogenetics provides testing through PCR, FISH, aCGH and soon SNP.
2. Genesis Genetics is located in Detroit. Dr. Mark Hughes, its founder and medical director has been a leader in the field of genetics, specializing in the diagnosis of single gene disorders.
3. Reproductive Genetics Institute (RGI) is in Chicago. They also have a special focus in single gene disorders and an emphasis on polar body biopsy.
4. Natera is a California-based genetics lab that uses the SNP assay of each parent and compares it with each embryo to generate a calculation of whether the embryo is normal or not. SNP assays have the same advantage of CGH in that the whole genome is analyzed. ICSI is also required. Natera also utilizes information SNP analysis from each parent to interpret the data from the embryo.
| Type of Test | Indication | Is ICSI Required? | Day of Biopsy | Genetics Reference Lab |
| PCR DNA amplification technique |
Single gene disorders | Yes | Typically Day 3 with fresh transfer |
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| FISH Detection of chromosome number (limited to 12 of the 23 chromosomes) |
Chromosomal Problems and Gender | No | Day 3 with fresh transfer or Day 5 biopsy with frozen transfer |
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| CGH Detection of chromosome number (all 23) |
Chromosomal Problems | Yes | Day 3 with fresh transfer or Day 5 biopsy with frozen transfer |
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| SNPWhole genome analysis | Single gene disorders and chromosomal problems | Yes | Day 3 with fresh transfer Day 5 biopsy with frozen transfer |
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Dr. Weckstein talks to Fertility Authority
Progressive Fertility Treatments to Enhance Chances of Conception
Established in 1983, just two years after the first successful birth through in vitro fertilization (IVF) in the United States, the Reproductive Science Center of the San Francisco Bay Area has been a pioneering fertility medical practice for more than a quarter-century. RSC was also responsible for the nation’s second successful birth of a baby from a frozen embryo and is recognized today for its pregnancy rates and work with egg donors and egg donation for patients from northern California, the Western United States, Asia, India and around the world for patients pursuing medical tourism.
Our fertility clinics in San Ramon, Orinda, San Jose and Modesto are easily accessible to fertility patients from Contra Costa County, Alameda County, Santa Clara County, San Francisco County, Stanislaus County, Solano County, Merced County, Mariposa County, Calaveras County, Eldorado County, Placer County, San Benito County and Monterey County. Fertility doctors Dr. Weckstein, Dr. Willman, Dr. Hinckley, Dr. Sgarlata, Dr. Wachs and Dr. Ivani are specialists in infertility, recurrent pregnancy loss, polycystic ovary syndrome (PCOS), endometriosis, miscarriages, male infertility, pre-implantation genetic screening (PGS), egg freezing and reproductive medicine surgery.
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