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A Woman’s diet during pregnancy is very important, especially when it comes to cholesterol.

It’s always wonderful when our infertility patients become pregnant. Like all mothers to be, they want to know what they should do to take care of their precious pregnancy, and diet is often a first concern. Many women ask me if they have to watch what they eat, now that their diet is a factor in two lives.

The answer is yes, as a general principle in a healthy pregnancy. However, women with high cholesterol levels should be particularly careful about what they eat during pregnancy. At Reproductive Science Center we check cholesterol panels on all women over 40 years old and in women with polycystic ovary syndrome (PCOS) and obesity, as cholesterol levels are usually higher among these groups of women. High cholesterol can run in families and can be elevated even in otherwise healthy women.

We know that lipid (fat) levels increase during pregnancy, so if you have high levels of lipids (cholesterol is a type of lipid) before you conceive, be very careful when you become pregnant. Doctors are just beginning to understand the associations between lipid levels and pregnancy outcomes.

High levels of triglycerides, which are another type of lipid found in the blood, appear to double the risk of gestational diabetes and preeclampsia in pregnant women. These conditions are dangerous for both mother and child. This appears to be independent of body mass index, meaning this increased risk is not due to obesity.

Presently, medications to combat high triglyceride levels are usually not used during pregnancy, so diet and exercise are the mainstay of treatment. Reducing your triglycerides before pregnancy seems to be the best medicine.

How can you reduce triglyceride levels?

  • Reduce the amount of trans fats and saturated fats you consume (butter, oil, etc.)
  • Eat foods with less sugar
  • Choose whole-grain foods
  • Exercise at least 30 minutes daily
  • Limit alcoholic beverages

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Do a 90-day detox

Bet you didn’t know it takes somewhere between 75 and 90 days for sperm to form and mature before shooting out into the world. That means your guy needs to start taking care of his body at least three months before he starts thinking about making babies.

“Have him look at his lifestyle habits,” says RSCBA’s renowned reproductive endocrinologist Carmelo Sgarlata, MD. “You want him to be free of anything that could hinder sperm production. The goal is to have a healthy environment from the start.” Translation: If he only cuts back on drinking, smoking or junk food when you’re ovulating it won’t make much difference, but having him embrace an anti-inflammatory diet and an exercise routine on a daily basis leading up to when you plan to get pregnant will.

Go nuts—seriously

It turns out consuming healthy nuts leads to, well, healthy nuts! UCLA researchers studied more than 100 men to investigate the effect of eating walnuts. Three months later, the men’s semen quality was analyzed and showed that those who consumed 2.5 ounces each day had significantly increased levels of omega-3 fatty acids.

That translated into better sperm vitality, mobility and fewer chromosomal abnormalities. “Eating any type of nut could reduce oxidative stress in your body,” adds Sgarlata. “And, in turn, potentially improve sperm production.”

Make like a Mediterranean

Maintaining a healthy weight ups his chances to fertilize your egg. And while there are many ways to go about dropping pounds, his best bet is to follow the Mediterranean diet, which emphasizes plant-based foods including whole grains, greens and nuts as well as fish and poultry. “Consume five to six servings of fruits and veggies every day,” adds Sgarlata.

“Make sure you eat across the color spectrum—from eggplants to strawberries—to get the most antioxidants.” Just check that your produce is low in pesticide residue, which can negatively affect sperm quality. You’ll also want to cut back on processed meats, like bacon. One study showed that men who ate one to three servings per day had worse sperm quality. On the other hand, those who ate fish, especially fatty fish such as salmon, had 34 percent higher sperm count.

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At least once or twice a month, I see a patient who comes in for fertility treatment frustrated by the presence of an ovarian cyst.

Women may have a simple benign ovarian cyst which comes and goes without detection. However, a patient undergoing fertility treatment is more likely to have this cyst noticed because she is having frequent pelvic ultrasounds as part of her fertility treatment.

IVF treatment and cysts

When a cyst is seen, the patient must hold off on fertility medications for at least 1 to 2 months (which is frustrating when you are so anxious to get pregnant) These cysts can often be painful or annoying physically.

Clomid, Femara (letrozole), and even gonadotropin shots may make cysts appear more often. For some women, moving directly to IVF may help them conceive in a more efficient manner, not only by increasing their pregnancy rate per month but also by avoiding the necessary rest periods between treatment cycles.

But for the physician, these ovarian cysts must be evaluated as there is always a chance they are not just simple benign cysts but instead are precancerous or cancerous.

Ovarian cysts and cancer

In the United States, women have a 5-10% chance of undergoing surgery to evaluate an ovarian “mass” (cyst) but only approximately 15% of these patients are diagnosed with cancer.

Cancer is much more often seen in the postmenopausal age group, however, younger patients must also be evaluated as some could have cancer or precancerous cysts. Luckily, the majority of cysts in younger women are not Cancer. Non-cancerous cysts include endometriomas or ruptured hemorrhagic cysts. Tubal ovarian abscesses or ovarian torsion can also present with an ovarian mass or cyst appearance.

After a detailed history by a physician, an ultrasound should be performed. Worrisome features on ultrasounds include solid components, septations thicker than 2 to 3 mm, nodules, and vascular flow or ascites.

CT scan or MRI may also be used if ultrasound is equivocal.

Biomarkers in the blood may be helpful to decide whether to involve a gynecologic oncologist in the surgery, but should not be used alone to decide to undergo surgery.

CA-125 is the most well-studied biomarker but is very non-specific. HE4 may also be used to calculate the risk of malignancy in conjunction with CA-125.

A new test, OVA-1 may also be helpful in knowing whether to involve an oncologist in the surgery. For young women, germ cell markers (in the blood) may be more helpful including LDH, HCG, AFP, DHEA, AMH, INH B, estrogen, and testosterone.

Since the word “cyst” just means a fluid-filled sack, these are most often benign and will disappear on their own in time (or while a woman’s body “rests” on birth control pills). However, following up with your fertility doctor is necessary to keep you in optimal health.

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