Genetic Testing
Preimplantation genetic testing (PGT) is a cutting-edge tool in fertility care, offering individuals and couples the ability to test embryos for genetic and chromosomal conditions before they are transferred to the uterus during an IVF cycle.
Schedule an AppointmentWhat is Preimplantation
Genetic Testing?
Preimplantation genetic testing (PGT) is a cutting-edge tool in fertility care, offering individuals and couples the ability to test embryos for genetic and chromosomal conditions before they are transferred to the uterus during an IVF cycle. This advanced testing provides vital information that can:
- Increase the chances of a healthy pregnancy.
- Minimize the risk of miscarriage.
- Reduce the likelihood of passing on genetic conditions.
By combining PGT with a personalized treatment plan, patients can make informed decisions that align with their family-building goals.
PGT Steps
Embryo
Results
Best embryo is
What is the PGT process?
1. A cell biopsy from the tissue that will become the placenta is taken from an embryo for testing.
2. The test sample is placed in a tube and shipped to a genetic testing lab for analysis. Embryos remain at the Reproductive Science Center IVF center.
3. Testing results are sent within 10-14 days to your physician in a genetic report. Your physician will call to discuss the results and next steps.
4. The embryo(s) with the highest genetic quality are identified and one is transferred to the uterus. The transfer will occur in the following cycle. Patients receive medications to optimize the uterine lining and receptivity
Who Should Do Genetic Testing?
While genetic abnormalities can and do happen at any age, the prevalence increases as a woman approaches age 38 and beyond.
In addition to women with advanced maternal age, other candidates for PGT include those who have experienced two or more miscarriages with an unknown cause, chromosomal abnormalities in a previous pregnancy, two or more assisted reproductive cycles without a pregnancy, or a male infertility diagnosis indicating a low sperm concentration.
Types of Preimplantation
Genetic Testing
Preimplantation genetic testing for Aneuploidies (PGT-A)
Previously referred to as preimplantation genetic screening (PGS), PGT-A examines embryos for the correct number of chromosomes (euploid). This testing can improve implantation rates and reduce miscarriage risks.
Recommended for:
- Women in their late 30s or early 40s.
- Patients with a history of miscarriage.
- Those who have experienced failed IVF cycles.
Preimplantation genetic testing for Monogenic Disorders (PGT-M)
Formerly called preimplantation genetic diagnosis (PGD), PGT-M screens for specific genetic mutations within an embryo. This type of testing is essential for those with known hereditary conditions.
Recommended for:
- Patients with a diagnosed genetic disorder.
- Couples who are carriers of the same genetic condition.
- Individuals with a family history of a specific genetic condition.
Preimplantation genetic testing for Structural Rearrangements (PGT-SR)
Previously a subset of PGD, PGT-SR identifies structural abnormalities in chromosomes, such as translocations or inversions, that may lead to miscarriage or implantation failure.
Recommended for:
- Patients with recurrent miscarriages.
- Individuals diagnosed with a balanced translocation or chromosomal inversion.
